NFL Week One Odds: Seahawks vs. Patriots and Rams in Australia

You can now stream Fox News articles while you listen, but the real story this season is the slate of games waiting to start. Week one arrives loaded with excitement, headlined by a Sept. 9 rematch between the Seahawks and Patriots in London. The NFL also takes its first-ever steps into Australia that night, pitting the Rams against the 49ers.

Here are the specific lines available at DraftKings Sportsbook as of Sept. 7, so you know exactly where the odds sit before kickoff. This page contains affiliate links to legal sports betting partners. If you sign up or place a wager through those links, FOX Sports may receive compensation. Read more about Sports Betting on FOX Sports if you want details on how it works.

The action kicks off Wednesday, Sept. 9 with the Patriots visiting the Seahawks. The line gives the home team a spread of -3.5. You can find them at moneyline odds of -175, while the Patriots are listed as +145. The over/under for that clash is set at 44.5 points.

On Thursday, Sept. 10, the Rams host the 49ers in Australia. They hold a -3.5 spread advantage there. Moneyline odds show the Rams at -185 and the 49ers at +154. Bettors expecting a high-scoring affair will see an over/under of 48.5.

Sunday, Sept. 13 brings a full slate of games across the country. In New Orleans, the Saints travel to Detroit for a matchup where the Lions hold a -7 spread and moneyline odds of -305 against the Saints at +245. The over/under sits at 49.5 points.

In Jacksonville, the Browns head west to play the Jaguars. The line heavily favors the visitors with an -8.5 spread. Moneyline figures place the Jaguars at -440 and the Browns at +340. That game's total is set lower than usual at 40.5.

Chicago sends its Bears to Charlotte to face the Panthers. Chicago gets a -3 spread and moneyline odds of -148, while Carolina sits at +124. The projected total for this one is 46.5 points.

Buffalo plays in Houston that day with the Bills visiting the Texans. This is a tight contest on paper since the spread is only -1.5 for the home team and both sides sit at moneyline odds of -110. The over/under comes in at 44.5.

Baltimore travels to Indianapolis for a Week 1 showdown with the Colts. The Ravens hold the edge with a -3.5 spread and moneyline odds of -175, leaving Indiana as +145. Expect around 47.5 points according to the bookmakers.

Tampa Bay goes to Cincinnati to challenge the Bengals in another defensive battle. The Bengals are favored by 3.5 points at -205 on the moneyline, while Tampa sits at +170. The total for this game is a high 50.5 points.

Atlanta flies to Pittsburgh where the Steelers hold a -3.5 spread advantage with moneyline odds of -180 against Atlanta's +150. That contest projects to see 42.5 points scored in regulation.

New York visits Tennessee for a game where the Titans are favored by 1.5 points at -125, while the Jets sit as +105 on the moneyline. The over/under here is just 39.5 points.

Arizona travels to Los Angeles to play the Chargers in San Diego or SoCal depending on the venue setup for that specific matchup. Wait, they are playing at home. The Chargers hold a -10 spread with massive moneyline odds of -500 against Arizona's +380. That game projects to hit 47.5 points.

Washington hosts Philadelphia in another classic rivalry. The Eagles are favored by 4.5 points at -205, while Washington sits as +170 on the moneyline. The total for that one is set at 44.5.

Green Bay travels to Minnesota where the Vikings hold a narrow -1.5 spread advantage with moneyline odds of -122 against Green Bay's +102. The over/under sits right in the middle at 46.5 points.

Miami goes to Las Vegas for a game where the Raiders are favored by 3.5 points at -185, leaving Miami as +154 on the moneyline. That matchup projects for 40.5 points total.

Dallas travels East to play New York in what looks like a defensive grind given the low spread of -3 for Dallas and their moneyline odds of -162 against Giants at +136. The over/under is set at 48.5 points.

Monday night action lands on Sept. 14 with Denver visiting Kansas City. The Chiefs hold a -3 spread advantage with moneyline odds of -148, while Denver sits as +124. That week closer projects for 43.5 points to be scored before the lights go out in late September.